I enjoyed Juno. I went into it expecting a quirky comedy about teen pregnancy and wasn't disappointed. If you're expecting the "best movie of the year" you might be letdown as that is too much pressure to live up to.
On a couple of occasions the hipster slang got to me - too much all at once - but real-life highschoolers have their own lingo, and often people not of that age are annoyed by it.
As for a lost weekend's comments, aside from the colourful costumes and interiors, and the use of a Kink's song on the soundtrack, I don't see any Wes Anderson. There are no surrealist or farcical elements in Juno.
Hype wise, Juno reminds me a lot of "My Big Fat Greek Wedding" - a movie that got a lot of buzz, tons of people went to see it, some thought it was hilarious while others thought it was too "ethnic". Juno is a comedy about teen pregnancy, so if you can't see humour in the situation and think the subject should be dealt with seriously, then you'll probably be disappointed.